Early Stage Researchers

Design, synthesis and evaluation of antagonists towards Bc2L-C

Design of antagonists of LecB and LecB like lectins

Design, synthesis and evaluation of multivalent antagonists for propeller lectins

Characterisation of lectins from emerging fungi and identification from fungal extracts

Synthesis of a diversity library of glycomimetics: towards a glycomimetic chip for drug discovery in glycomedicine

Discovery of galectin-8 antagonists

Structure-based design, synthesis and biological evaluation of novel ligands targeting selected galectin-8

Identification of potent and selective drug-like ligands for therapeutically relevant siglecs

Design of peptido/glyco-mimetic inhibitors of GlcNAcylating protein OGT

Structure-based design and synthesis of novel inhibitors of GlcNAcylating protein OGT

Discovery of inhibitors of bacterial sialic acid sodium solute symporters

Investigation of pharmacokinetic properties of lectin ligands to improve their oral availability